- Under construction as of May 07
- Description: uses adaptive optics technology with confocal focusing
capabilities to correct optical imperfections in the human eye and
noninvasively obtain images of individual cells in the living retina
with a lateral resolution (~ 2 microns) that is at least 2 to 4 times
better than that of current clinical instruments. This instrument will
provide real-time imaging of the retina in depth along with significant
improvements in retinal image contrast due to the use of a confocal
aperture that rejects light scattered from objects outside the plane of
focus. Also, the addition of fluorescence imaging capabilities will
allow normally transparent cells (such as ganglion cells) that are
labeled with a fluorescent marker to emit visible light (or fluoresce)
when exposed to certain wavelengths of light. Imaging individual cells
in the living eye could enhance our ability to better understand and
diagnose blinding retinal diseases, such as glaucoma and different
macular degenerations, and importantly, to track the effectiveness of
potential treatments, such as precision laser surgery and gene
therapies.
- PI: Jason Porter
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